DAF-FM

• Catalog No.: D1821
• CAS Number: 254109-20-1
• M. F.: C21H14F2N2O5
• M. W.: 412.3430664
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-amino-2',7'-difluoro-3',6'-dihydroxy-5-(methylamino)-3H-spiro[2-benzofuran-1,9'-xanthene]-3-one
• IUPAC Traditional name: 4-amino-2',7'-difluoro-3',6'-dihydroxy-5-(methylamino)spiro[2-benzofuran-1,9'-xanthene]-3-one
• Synonyms: Diaminofluorescein-FM; 4-Amino-5-methylamino-2′,7′-difluorescein

DATABASE IDS

• CAS Number: 254109-20-1

PROPERTIES

• Empirical Formula (Hill Notation): C21H14F2N2O5
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: white to beige powder
• Solubility: DMSO: >1 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Caution
hygroscopic
Biochem/physiol Actions
DAF-FM is a highly sensitive, photo-stable fluorescent probe for the detection of nitric oxide (NO). DAF-2 is the original compound and is widely used, but DAF-FM is more sensitive to nitric oxide (NO) compared with DAF-2. DAF-FM is more photo-stable and less pH sensitive than DAF-2. DAF-FM is not quite as cell-permeable as the diacetate derivative, DAF-FM, but it does not need to be activated by cytosolic enzymes.

Description (简体中文)

Caution
hygroscopic
Biochem/physiol Actions
DAF-FM is a highly sensitive, photo-stable fluorescent probe for the detection of nitric oxide (NO). DAF-2 is the original compound and is widely used, but DAF-FM is more sensitive to nitric oxide (NO) compared with DAF-2. DAF-FM is more photo-stable and less pH sensitive than DAF-2. DAF-FM is not quite as cell-permeable as the diacetate derivative, DAF-FM, but it does not need to be activated by cytosolic enzymes.