Cyclo-Gly-Pro

• Catalog No.: C2374
• CAS Number: 3705-27-9
• M. F.: C7H10N2O2
• M. W.: 154.1665
• Purity: ≥98% (GC/HPLC)

SYNONYMS

• IUPAC name: octahydropyrrolo[1,2-a]piperazine-1,4-dione
• IUPAC Traditional name: hexahydropyrrolo[1,2-a]piperazine-1,4-dione
• Synonyms: Glycyl-L-proline lactam; cyclo-GP; (S)-3,6-Dioxohexahydropyrrolo[1,2-a]pyrazine; cyclo-Glycyl-L-Proline; cyclo-L-prolylglycine

DATABASE IDS

• MDL Number: MFCD01083707
• CAS Number: 3705-27-9

PROPERTIES

• Empirical Formula (Hill Notation): C7H10N2O2
• Purity: ≥98% (GC/HPLC)
• Apperance: powder
• Solubility: DMSO: >10 mg/mL
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cyclo-Gly-Pro is a neuro-protective compound, an endogenous diketopiperazine, which enhances memory. In the animal model of PD, the compound improved functional recovery when administered after the onset of dyskinesia. It appears that the compound recovery function may result from non-proliferative neurogenesis that results from the inhibition of apoptosis of stem cells and/or the promotion of neuronal-orientated proliferation in the SVZ (subventricular zone).

Description (简体中文)

Biochem/physiol Actions
Cyclo-Gly-Pro is a neuro-protective compound, an endogenous diketopiperazine, which enhances memory. In the animal model of PD, the compound improved functional recovery when administered after the onset of dyskinesia. It appears that the compound recovery function may result from non-proliferative neurogenesis that results from the inhibition of apoptosis of stem cells and/or the promotion of neuronal-orientated proliferation in the SVZ (subventricular zone).