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JNJ-1661010_Molecular_structure_CAS_)
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JNJ-1661010

Catalog No. J3205 Name Sigma Aldrich
CAS Number Website http://www.sigmaaldrich.com
M. F. C19H19N5OS Telephone 1-800-521-8956
M. W. 365.45206 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154561

SYNONYMS

IUPAC name
N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide
IUPAC Traditional name
N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide

DATABASE IDS

MDL Number MFCD00209157

PROPERTIES

Empirical Formula (Hill Notation) C19H19N5OS
Purity ≥98% (HPLC)
Apperance solid
Solubility DMSO: ≥28 mg/mL
MSDS Link Download
Storage Temperature 2-8°C
German water hazard class 1

DETAILS

Description (English)
Biochem/physiol Actions
JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.
Description (简体中文)
Biochem/physiol Actions
JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.

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