JNJ-1661010

• Catalog No.: J3205
• M. F.: C19H19N5OS
• M. W.: 365.45206
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide
• IUPAC Traditional name: N-phenyl-4-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine-1-carboxamide

DATABASE IDS

• MDL Number: MFCD00209157

PROPERTIES

• Empirical Formula (Hill Notation): C19H19N5OS
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: ≥28 mg/mL
• Storage Temperature: 2-8°C
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.

Description (简体中文)

Biochem/physiol Actions
JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.