(E)-Guggulsterone

• Catalog No.: G4923
• CAS Number: 39025-24-6
• M. F.: C21H28O2
• M. W.: 312.44582
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: (1S,2R,10R,11S,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-5,13-dione
• IUPAC Traditional name: (1S,2R,10R,11S,15S)-14-ethylidene-2,15-dimethyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadec-6-ene-5,13-dione
• Synonyms: (17E)-Pregna-4,17(20)-diene-3,16-dione

DATABASE IDS

• CAS Number: 39025-24-6
• MDL Number: MFCD01310758

PROPERTIES

• Empirical Formula (Hill Notation): C21H28O2
• Purity: ≥95% (HPLC)
• Apperance: white to off-white powder
• Solubility: DMSO: soluble5 mg/mL
• European Hazard Symbols: Irritant (Xi)
• Risk Statements: 37
• Safety Statements: 36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.1. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.2

Description (简体中文)

Biochem/physiol Actions
Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.1. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.2