NBI-31772 hydrate

• Catalog No.: N8289
• CAS Number: 374620-70-9(anhydrous)
• M. F.: C17H13NO8
• M. W.: 359.28702
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• IUPAC name: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid hydrate
• IUPAC Traditional name: 1-(3,4-dihydroxybenzoyl)-6,7-dihydroxyisoquinoline-3-carboxylic acid hydrate

DATABASE IDS

• CAS Number: 374620-70-9(anhydrous)
• MDL Number: MFCD20274527

PROPERTIES

• Empirical Formula (Hill Notation): C17H11NO7 · xH2O
• Purity: ≥98% (HPLC)
• Apperance: solid
• Storage Condition: protect from light
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
NBI-31772 is an insulin-like growth factor-1 binding proteins (IGFBPs) inhibitor; IGF-1 potentiator. NBI-31772 is an air/DMSO DOPA oxidation product, which inhibits IGF binding to IFGFB′s. NBI-31772 displaces IGF-1 from IGF1:IGFBP complex. Thus, it increases circulating level of IGF-1. NBI-31772 does not bind to IGFR.

Description (简体中文)

Biochem/physiol Actions
NBI-31772 is an insulin-like growth factor-1 binding proteins (IGFBPs) inhibitor; IGF-1 potentiator. NBI-31772 is an air/DMSO DOPA oxidation product, which inhibits IGF binding to IFGFB′s. NBI-31772 displaces IGF-1 from IGF1:IGFBP complex. Thus, it increases circulating level of IGF-1. NBI-31772 does not bind to IGFR.