S-2E

• Catalog No.: S6445
• CAS Number: 155730-92-0
• M. F.: C22H25NO4
• M. W.: 367.4382
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-{[(3S)-1-(4-tert-butylphenyl)-5-oxopyrrolidin-3-yl]methoxy}benzoic acid
• IUPAC Traditional name: 4-{[(3S)-1-(4-tert-butylphenyl)-5-oxopyrrolidin-3-yl]methoxy}benzoic acid
• Synonyms: (S)-(+)-4-[1-(4-tert-Butylphenyl)-2-oxo-pyrrolidin-4-yl]methoxybenzoic acid

DATABASE IDS

• PubChem SID: 24724620
• MDL Number: MFCD06407742
• CAS Number: 155730-92-0

PROPERTIES

• Empirical Formula (Hill Notation): C22H25NO4
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: DMSO: soluble11 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Packaging
Shipped ambient under nitrogen.
Biochem/physiol Actions
HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. In the liver, S-2E is converted into its active metabolite, S-2E-CoA. S-2E-CoA noncompetitively inhibited the enzymatic activities of both 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase and acetyl-CoA carboxylase at K(i)=18.11 microM and K(i)=69.2 microM, respectively.

Description (简体中文)

包装
Shipped ambient under nitrogen.
Biochem/physiol Actions
HMG-CoA reductase and acetyl-CoA carboxylase inhibitor. In the liver, S-2E is converted into its active metabolite, S-2E-CoA. S-2E-CoA noncompetitively inhibited the enzymatic activities of both 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductase and acetyl-CoA carboxylase at K(i)=18.11 microM and K(i)=69.2 microM, respectively.