STO-609-acetic acid

• Catalog No.: S1318
• M. F.: C21H14N2O5
• M. W.: 374.34626
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: 11-oxo-3,10-diazapentacyclo[10.7.1.0^2,^1^0.0^4,^9.0^1^6,^2^0]icosa-1(20),2,4(9),5,7,12,14,16,18-nonaene-17-carboxylic acid; acetic acid
• IUPAC Traditional name: 11-oxo-3,10-diazapentacyclo[10.7.1.0^2,^1^0.0^4,^9.0^1^6,^2^0]icosa-1(20),2,4(9),5,7,12,14,16,18-nonaene-17-carboxylic acid; acetic acid
• Synonyms: 7-Oxo-7H-benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid - acetic acid

DATABASE IDS

• MDL Number: MFCD06411456

PROPERTIES

• Empirical Formula (Hill Notation): C19H10N2O3 · C2H4O2
• Purity: ≥95% (HPLC)
• Apperance: solid
• Melting Point: >300 °C
• Solubility: DMSO: soluble15 mg/mL at ≥60 °C
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

General description
1:1 adduct with acetic acid
Biochem/physiol Actions
Selective Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) antagonist. Inhibits CamKKa and CaMKKb with Ki = 80 and 15 ng/mL, respectively. Does not inhibit downstream CaM kinases (CaMKI and CaMKIV).

Description (简体中文)

General description
1:1 adduct with acetic acid
Biochem/physiol Actions
Selective Ca2+/Calmodulin-dependent protein kinase kinase (CaM-KK) antagonist. Inhibits CamKKa and CaMKKb with Ki = 80 and 15 ng/mL, respectively. Does not inhibit downstream CaM kinases (CaMKI and CaMKIV).