Miltefosine

• Catalog No.: M5571
• CAS Number: 58066-85-6
• M. F.: C21H46NO4P
• M. W.: 407.568001
• Purity: ≥98% (perchloric acid titration)

SYNONYMS

• IUPAC name: hexadecyl 2-(trimethylazaniumyl)ethyl phosphate
• IUPAC Traditional name: miltex
• Synonyms: Hexadecyl phosphocholine; HePC; Choline hexadecyl phosphate

DATABASE IDS

• MDL Number: MFCD00133396
• CAS Number: 58066-85-6

PROPERTIES

• Description: zwitterionic
• Empirical Formula (Hill Notation): C21H46NO4P
• Purity: ≥98% (perchloric acid titration)
• Solubility: H2O: soluble10 mg/mL, clear, colorless
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H334
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P261-P301 + P310-P342 + P311
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 22-43
• RTECS: KH2890000
• Safety Statements: 36/37
• Storage Temperature: room temp
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of protein kinase C and of phosphatidylcholine synthesis. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5571.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Description (简体中文)

Biochem/physiol Actions
Inhibitor of protein kinase C and of phosphatidylcholine synthesis. Used for the treatment of visceral and cutaneous leishmaniasis. Active against metronidazole-resistant and -susceptible strains of Trichomonas vaginalis1
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. M5571.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.