Pravastatin sodium salt hydrate

• Catalog No.: P4498
• CAS Number: 81131-70-6(anhydrous)
• M. F.: C23H35NaO7
• M. W.: 446.50957
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: sodium (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoate
• IUPAC Traditional name: sodium pravastatin(1-)
• Synonyms: Eptastatin sodium salt hydrate; (βR, δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β, δ,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic acid sodium hydrate

DATABASE IDS

• MDL Number: MFCD00887601
• CAS Number: 81131-70-6(anhydrous)

PROPERTIES

• Empirical Formula (Hill Notation): C23H35O7Na · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Melting Point: 171.2-173 °C
• Solubility: H2O: >10 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: QJ7185000
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Inhibits cholesterol synthesis in vivo (Ki ~1 nM).

Description (简体中文)

Biochem/physiol Actions
Competitive, water-soluble 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor. Inhibits cholesterol synthesis in vivo (Ki ~1 nM).