CKI-7 dihydrochloride

• Catalog No.: C0742
• CAS Number: 1177141-67-1
• M. F.: C11H14Cl3N3O2S
• M. W.: 358.67176
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide dihydrochloride
• IUPAC Traditional name: C11H12ClN3O2S dihydrochloride
• Synonyms: N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride

DATABASE IDS

• CAS Number: 1177141-67-1
• MDL Number: MFCD00897689
• PubChem SID: 24724430

PROPERTIES

• Empirical Formula (Hill Notation): C11H12ClN3O2S · 2HCl
• Purity: ≥98% (HPLC)
• Apperance: white to light tan solid
• Solubility: H2O: >5 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H301
• European Hazard Symbols: Toxic (T)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P301 + P310
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 25
• Safety Statements: 45
• Storage Condition: desiccated
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Caution
Material is hygroscopic
Biochem/physiol Actions
CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.

Description (简体中文)

Caution
Material is hygroscopic
Biochem/physiol Actions
CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC50 = 6 μM.