Ro4368554

• Catalog No.: R8782
• CAS Number: 478082-99-4
• M. F.: C19H21N3O2S
• M. W.: 355.45394
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
• IUPAC Traditional name: 3-(benzenesulfonyl)-7-(4-methylpiperazin-1-yl)-1H-indole
• Synonyms: 3-benzenesulfonyl-7-(4-methyl-piperazin-1-yl)-1H-indole; 7-(4-methyl-1-piperazinyl)-3-(phenylsulfonyl)-1H-Indole

DATABASE IDS

• CAS Number: 478082-99-4
• MDL Number: MFCD16875430

PROPERTIES

• Empirical Formula (Hill Notation): C19H21N3O2S
• Purity: ≥98% (HPLC)
• Apperance: off-white powder
• Solubility: DMSO: >10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: room temp
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).

Description (简体中文)

Biochem/physiol Actions
Ro4368554 is a 5-HT6 receptor antagonist. RO4368554 acts selectively at 5-HT6 receptors where it binds with a greater than 100-fold selectivity over other monoamine receptor subtypes (-log M pKi = 9.4 at 5-HT6 and 7.1 at 5-HT2A).