Chelidonine

• Catalog No.: 54274
• CAS Number: 476-32-4
• M. F.: C20H19NO5
• M. W.: 353.36856
• Purity: ≥97.0% (HPLC)

SYNONYMS

• IUPAC name: (1S,12S,13R)-24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11.0.0^2,^1^0.0^4,^8.0^1^4,^2^2.0^1^7,^2^1]tetracosa-2,4(8),9,14(22),15,17(21)-hexaen-12-ol
• IUPAC Traditional name: chelidonine
• Synonyms: Stylophorin

DATABASE IDS

• EC Number: 207-504-1
• CAS Number: 476-32-4
• MDL Number: MFCD00069660

PROPERTIES

• Empirical Formula (Hill Notation): C20H19NO5
• Impurities: ~5% water
• Purity: ≥97.0% (HPLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H312-H332
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P280
• Risk Statements: 20/21/22
• RTECS: FL9450000
• Safety Statements: 36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibits tubulin polymerisation (IC50=24 μM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.

Description (简体中文)

Biochem/physiol Actions
Inhibits tubulin polymerisation (IC50=24 μM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.