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PP121_Molecular_structure_CAS_1092788-83-4)
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PP121

Catalog No. P0036 Name Sigma Aldrich
CAS Number 1092788-83-4 Website http://www.sigmaaldrich.com
M. F. C17H17N7 Telephone 1-800-521-8956
M. W. 319.36378 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 5680

SYNONYMS

IUPAC name
1-cyclopentyl-3-{1H-pyrrolo[2,3-b]pyridin-5-yl}-1H-pyrazolo[3,4-d]pyrimidin-4-amine
IUPAC Traditional name
1-cyclopentyl-3-{1H-pyrrolo[2,3-b]pyridin-5-yl}pyrazolo[3,4-d]pyrimidin-4-amine
Synonyms
1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

DATABASE IDS

CAS Number 1092788-83-4
MDL Number MFCD12912434

PROPERTIES

Empirical Formula (Hill Notation) C17H17N7
Purity ≥98% (HPLC)
Apperance off-white powder
Solubility DMSO: >10 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
RID/ADR UN 2811 6.1/PG 3
Risk Statements 22
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 1

DETAILS

Description (English)
Biochem/physiol Actions
PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.
Description (简体中文)
Biochem/physiol Actions
PP121 is a dual inhibitor of tyrosine and phosphoinositide kinases. PP121 is the first inhibitor active on both Tyrosine kinases and the phosphatidylinositol-3-OH kinase (PI(3)K) family. The inhibitor is not effecting other serine-threonine protein kinases.

REFERENCES