Microcystin YR from Microcystis aeruginosa

• Catalog No.: M4069
• CAS Number: 101064-48-6
• M. F.: C52H72N10O13
• M. W.: 1045.18728

SYNONYMS

• IUPAC name: (5R,8S,11R,12R,15S,18S,19S,22R)-15-(3-carbamimidamidopropyl)-8-[(4-hydroxyphenyl)methyl]-18-[(5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,5,12,19-tetramethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid
• IUPAC Traditional name: (5R,8S,11R,12R,15S,18S,19S,22R)-15-(3-carbamimidamidopropyl)-8-[(4-hydroxyphenyl)methyl]-18-[(5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl]-1,5,12,19-tetramethyl-2-methylidene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid

DATABASE IDS

• PubChem SID: 24896901
• MDL Number: MFCD00236437
• CAS Number: 101064-48-6

PROPERTIES

• Empirical Formula (Hill Notation): C52H72N10O13
• Apperance: white powder
• Solubility: methanol: soluble2 mg/mL ((further dilute to 10% (v/v) methanol))
• Solubility: DMSO: soluble
• Solubility: ethanol: soluble
• GHS Signal Word: Danger
• GHS Hazard statements: H300-H310-H315-H317-H319-H330-H335
• European Hazard Symbols: Highly toxic (T+)
• Personal Protective Equipment: Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
• GHS Precautionary statements: P260-P264-P280-P284-P301 + P310-P302 + P350
• RID/ADR: UN 2811 6.1/PG 1
• Risk Statements: 26/27/28-36/37/38-43
• RTECS: GT4010000
• Safety Statements: 26-36/37/39-45
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 1
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Microcystin YR inhibits protein phosphatase type 2A and protein phosphatase type 1. Toxicity to undifferentiated cells was seen by inhibition of neutral red uptake, >80% at 100 μM, after 48 h.1

Description (简体中文)

Biochem/physiol Actions
Microcystin YR inhibits protein phosphatase type 2A and protein phosphatase type 1. Toxicity to undifferentiated cells was seen by inhibition of neutral red uptake, >80% at 100 μM, after 48 h.1