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Clofarabine

Catalog No. C7495 Name Sigma Aldrich
CAS Number 123318-82-1 Website http://www.sigmaaldrich.com
M. F. C10H11ClFN5O3 Telephone 1-800-521-8956
M. W. 303.6774432 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 513

SYNONYMS

IUPAC name
(2R,3R,4S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol
IUPAC Traditional name
clofarabine
Synonyms
(2R,3R,4S,5R)-5-(6-amino-2-chloropurin-9-yl)-4-fluoro-2-(hydroxymethyl)oxolan-3-ol, 2-chloro-2′-arabino-fluoro-2′-deoxyadenosine

DATABASE IDS

MDL Number MFCD00871077
CAS Number 123318-82-1

PROPERTIES

Empirical Formula (Hill Notation) C10H11ClFN5O3
Purity ≥98% (HPLC)
Apperance white powder
Solubility DMSO: >10 mg/mL
GHS Pictograms GHS06
GHS Signal Word Danger
GHS Hazard statements H300
European Hazard Symbols Toxic Toxic (T)
MSDS Link Download
Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
GHS Precautionary statements P264-P301 + P310
RID/ADR UN 2811 6.1/PG 3
Risk Statements 25
RTECS UD7473000
Safety Statements 45
Storage Temperature 2-8°C
Hazard Class 6.1
UN Number 2811
Packing Group 3
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
Clofarabine is a purine nucleoside antimetabolite. Clofarabine is toxic to nondividing lymphocytes and monocytes.
Description (简体中文)
Biochem/physiol Actions
Clofarabine is a purine nucleoside antimetabolite. Clofarabine is toxic to nondividing lymphocytes and monocytes.

REFERENCES