Estramustine sodium phosphate

• Catalog No.: E0407
• CAS Number: 52205-73-9
• M. F.: C23H34Cl2NNa2O8P
• M. W.: 600.377261

SYNONYMS

• IUPAC name: disodium (1S,10R,11S,14S,15S)-14-hydroxy-15-methyltetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-2,4,6-trien-5-yl N,N-bis(2-chloroethyl)carbamate hydrate hydrogen phosphate
• IUPAC Traditional name: disodium estramustine hydrate hydrogen phosphate
• Synonyms: Estra-1,3,5(10)triene-3,17β-diol 3-[N,N-bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate) sodium salt; Estradiol 3-bis(2-chloroethyl)carbamate 17-(dihydrogen phosphate) sodium salt

DATABASE IDS

• EC Number: 257-735-7
• CAS Number: 52205-73-9

PROPERTIES

• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 37
• RTECS: KG7350000
• Safety Statements: 26
• Storage Temperature: room temp
• German water hazard class: 3
• European Hazard Symbols: Irritant (Xi)
• Empirical Formula (Hill Notation): C23H30Cl2NNa2O6P
• Solubility: H2O: soluble50 mg/mL

DETAILS

Description (English)

Biochem/physiol Actions
Estradiol mustard prodrug, which binds estradiol receptors irreversibly. Highly effective in treatment of advanced metastatic prostate cancer.1 Depolymerizes microtubules by binding to microtubule associated proteins (MAPs).

Description (简体中文)

Biochem/physiol Actions
Estradiol mustard prodrug, which binds estradiol receptors irreversibly. Highly effective in treatment of advanced metastatic prostate cancer.1 Depolymerizes microtubules by binding to microtubule associated proteins (MAPs).