BSc3094 monohydrobromide

• Catalog No.: B7937
• M. F.: C17H13BrN6O3S
• M. W.: 461.29252
• Purity: ≥98% (HPLC)
• Storage: protect from light

SYNONYMS

• IUPAC name: N'-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-1H-1,3-benzodiazole-5-carbohydrazide hydrobromide
• IUPAC Traditional name: N'-[4-(4-nitrophenyl)-1,3-thiazol-2-yl]-1H-1,3-benzodiazole-5-carbohydrazide hydrobromide
• Synonyms: 2-[4-(4-Nitrophenyl)-2-thiazolyl]hydrazide-1H-benzimidazole-6-carboxylic acid monohydrobromide

DATABASE IDS

• MDL Number: MFCD12912398

PROPERTIES

• Empirical Formula (Hill Notation): C17H12N6O3S·HBr
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: soluble22 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H319
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22-36
• Safety Statements: 26
• Storage Condition: protect from light
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
BSc3094 is a potent inhibitor of tau aggregation and dissolves preformed tau paired helical filaments. BSc3094 interacts closely with the tau protein at the edge involving protons I-IV, while the second attachment site seems to be at the nitro group. In N2A cells (model system for tau aggregation), BSc3094 exhibited low toxicity.

Description (简体中文)

Biochem/physiol Actions
BSc3094 is a potent inhibitor of tau aggregation and dissolves preformed tau paired helical filaments. BSc3094 interacts closely with the tau protein at the edge involving protons I-IV, while the second attachment site seems to be at the nitro group. In N2A cells (model system for tau aggregation), BSc3094 exhibited low toxicity.