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PalGly_Molecular_structure_CAS_2441-41-0)
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PalGly

Catalog No. P0064 Name Sigma Aldrich
CAS Number 2441-41-0 Website http://www.sigmaaldrich.com
M. F. C18H35NO3 Telephone 1-800-521-8956
M. W. 313.4754 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 3118

SYNONYMS

IUPAC name
2-hexadecanamidoacetic acid
IUPAC Traditional name
N-palmitoyl glycine
Synonyms
N-palmitoyl glycine
Hexadecanoylaminoacetic acid

DATABASE IDS

MDL Number MFCD00153471
CAS Number 2441-41-0

PROPERTIES

Empirical Formula (Hill Notation) C18H35NO3
Purity ≥98% (HPLC)
Apperance white to off-white solid
Solubility DMSO: >10 mg/mL
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)
Storage Temperature 2-8°C
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.
Description (简体中文)
Biochem/physiol Actions
PalGly is an endogenous signaling lipid that modulates calcium influx and nitric oxide production. PalGly inhibits heat-evoked firing of wide dynamic range (WDR) neurons, activates calcium influx in DRG cells and stimulates NO production. Preliminary studies suggest its signaling mechanism involves GPCR-mediated cation channel activation and a Gαi/o-coupled signaling pathway, which is being further investigated.

REFERENCES