GW4064

• Catalog No.: G5172
• CAS Number: 278779-30-9
• M. F.: C28H22Cl3NO4
• M. W.: 542.83758
• Purity: ≥98% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: 3-[2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
• IUPAC Traditional name: 3-[2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-isopropyl-1,2-oxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid
• Synonyms: 3-(2,6-Dichlorophenyl)-4-(3’-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole

DATABASE IDS

• MDL Number: MFCD09971006
• CAS Number: 278779-30-9

PROPERTIES

• Empirical Formula (Hill Notation): C28H22Cl3NO4
• Purity: ≥98% (HPLC)
• Apperance: white powder
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H319-H413
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 22-36
• Safety Statements: 26
• Storage Condition: desiccated
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
GW4064 is a FXR agonist. GW4064 is a potent (EC50 = 15 nM), non-steroidal agonist of the orphan nuclear receptor FXR. It shows no activity on other nuclear receptors including RAR up to 1 mM. This is an important tool for the study of the involvment of FXR in a variety of biological activities.

Description (简体中文)

Biochem/physiol Actions
GW4064 is a FXR agonist. GW4064 is a potent (EC50 = 15 nM), non-steroidal agonist of the orphan nuclear receptor FXR. It shows no activity on other nuclear receptors including RAR up to 1 mM. This is an important tool for the study of the involvment of FXR in a variety of biological activities.