Nutlin-3

• Catalog No.: N6287
• CAS Number: 548472-68-0
• M. F.: C30H30Cl2N4O4
• M. W.: 581.4896
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-[4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1-carbonyl]piperazin-2-one
• IUPAC Traditional name: 4-[4,5-bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxyphenyl)-4,5-dihydroimidazole-1-carbonyl]piperazin-2-one
• Synonyms: (±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one

DATABASE IDS

• PubChem SID: 24724554
• MDL Number: MFCD07784509
• CAS Number: 548472-68-0

PROPERTIES

• Empirical Formula (Hill Notation): C30H30Cl2N4O4
• Purity: ≥98% (HPLC)
• Shipped in: wet ice
• Apperance: powder
• Solubility: DMSO: soluble20 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Nutlin-3 is a Mdm2 (mouse double minute 2) antagonist, p53 pathway activator, and apoptosis inducer.
Legal Information
Sold under license from Hoffman-La Roche, Inc. US patent 6,734,302.

Description (简体中文)

Biochem/physiol Actions
Nutlin-3 is a Mdm2 (mouse double minute 2) antagonist, p53 pathway activator, and apoptosis inducer.
Legal Information
Sold under license from Hoffman-La Roche, Inc. US patent 6,734,302.