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5-AIQ hydrochloride_Molecular_structure_CAS_93117-07-8)
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5-AIQ hydrochloride

Catalog No. A7479 Name Sigma Aldrich
CAS Number 93117-07-8 Website http://www.sigmaaldrich.com
M. F. C9H9ClN2O Telephone 1-800-521-8956
M. W. 196.63356 Fax
Purity ≥97% (HPLC) Email
Storage Chembase ID: 154418

SYNONYMS

IUPAC name
5-amino-1,2-dihydroisoquinolin-1-one hydrochloride
IUPAC Traditional name
5-amino-2H-isoquinolin-1-one hydrochloride
Synonyms
5-Aminoisoquinolinone hydrochloride

DATABASE IDS

PubChem SID 24724396
MDL Number MFCD03452659
CAS Number 93117-07-8

PROPERTIES

Empirical Formula (Hill Notation) C9H9ClN2O
Purity ≥97% (HPLC)
Apperance tan solid
Solubility DMSO: >20 mg/mL
Solubility H2O: >20 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36
Storage Temperature -20°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1).
Application
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). 5-AIQ hydrochloride was used in a study that determined PARP inhibitors have antiangiogenic effects, which may have tremendous clinical implications for the treatment of various cancers and certain retinopathies.
Description (简体中文)
Biochem/physiol Actions
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1).
Application
5-AIQ hydrochloride is an inhibitor of poly (ADP-ribose) polymerase-1 (PARP-1). 5-AIQ hydrochloride was used in a study that determined PARP inhibitors have antiangiogenic effects, which may have tremendous clinical implications for the treatment of various cancers and certain retinopathies.

REFERENCES