Reversine

• Catalog No.: R3904
• CAS Number: 656820-32-5
• M. F.: C21H27N7O
• M. W.: 393.48538
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 6-N-cyclohexyl-2-N-[4-(morpholin-4-yl)phenyl]-7H-purine-2,6-diamine
• IUPAC Traditional name: reversine
• Synonyms: 2-(4-Morpholinoanilino)-6-cyclohexylaminopurine

DATABASE IDS

• MDL Number: MFCD07784513
• PubChem SID: 24724590
• CAS Number: 656820-32-5

PROPERTIES

• Empirical Formula (Hill Notation): C21H27N7O
• Purity: ≥98% (HPLC)
• Gene Information: human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora3(25370)
• Apperance: solid
• Solubility: DMSO: soluble7 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.

Description (简体中文)

Biochem/physiol Actions
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.