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Reversine

Catalog No. R3904 Name Sigma Aldrich
CAS Number 656820-32-5 Website http://www.sigmaaldrich.com
M. F. C21H27N7O Telephone 1-800-521-8956
M. W. 393.48538 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 4991

SYNONYMS

IUPAC name
6-N-cyclohexyl-2-N-[4-(morpholin-4-yl)phenyl]-7H-purine-2,6-diamine
IUPAC Traditional name
reversine
Synonyms
2-(4-Morpholinoanilino)-6-cyclohexylaminopurine

DATABASE IDS

MDL Number MFCD07784513
PubChem SID 24724590
CAS Number 656820-32-5

PROPERTIES

Empirical Formula (Hill Notation) C21H27N7O
Purity ≥98% (HPLC)
Gene Information human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora3(25370)
Apperance solid
Solubility DMSO: soluble7 mg/mL
Solubility H2O: insoluble
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H302
European Hazard Symbols Harmful Harmful (Xn)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Risk Statements 22
Storage Temperature 2-8°C
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.
Description (简体中文)
Biochem/physiol Actions
Reversine is a potent, selective human A3 adenosine receptor antagonist with a Ki value of 0.66 μM. Synthetic substituted purine implicated in cellular regeneration; induces differentiated myogenic-lineage-committed cells to become multipotent mesenchymal progenitor cells.

REFERENCES