Eplerenone

• Catalog No.: E6657
• CAS Number: 107724-20-9
• M. F.: C24H30O6
• M. W.: 414.4914
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: methyl (1'R,2R,2'S,9'R,10'R,11'S,15'S,17'R)-2',15'-dimethyl-5,5'-dioxo-18'-oxaspiro[oxolane-2,14'-pentacyclo[8.8.0.0^1,^1^7.0^2,^7.0^1^1,^1^5]octadecan]-6'-ene-9'-carboxylate
• IUPAC Traditional name: eplerenone
• Synonyms: 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, methyl ester; SC-66110; Inspra; Cgp 30083; HSDB 7522; Eplerenone [USAN]; Epoxymexrenone; Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, gamma-lactone, methyl ester, (7alpha,11alpha,17alpha)-

DATABASE IDS

• CAS Number: 107724-20-9

PROPERTIES

• Empirical Formula (Hill Notation): C24H30O6
• Purity: ≥98% (HPLC)
• Apperance: white to beige powder
• Solubility: DMSO: soluble2 mg/mL, clear (warmed)
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Eplerenone is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone (S3378), having lower affinity for progesterone, androgen, and glucocorticoid receptors.

Description (简体中文)

Biochem/physiol Actions
Eplerenone is an aldosterone antagonist more specific for the mineralocorticoid receptor than spironolactone (S3378), having lower affinity for progesterone, androgen, and glucocorticoid receptors.