GW441756 hydrochloride

• Catalog No.: G3420
• CAS Number: 504433-24-3(freebase)
• M. F.: C17H14ClN3O
• M. W.: 311.76556
• Purity: ≥97% (HPLC)

SYNONYMS

• IUPAC name: 3-[(1-methyl-1H-indol-3-yl)methylidene]-1H,2H,3H-pyrrolo[3,2-b]pyridin-2-one hydrochloride
• IUPAC Traditional name: 3-[(1-methylindol-3-yl)methylidene]-1H-pyrrolo[3,2-b]pyridin-2-one hydrochloride
• Synonyms: 1,3-Dihydro-3-[(1-methyl-1H-indol-3-yl)methylene]-2H-pyrrolo[3,2-b]pyridin-2-one hydrochloride

DATABASE IDS

• CAS Number: 504433-24-3(freebase)
• PubChem SID: 24895126
• MDL Number: MFCD07370136

PROPERTIES

• Empirical Formula (Hill Notation): C17H13N3O · HCl
• Purity: ≥97% (HPLC)
• Apperance: powder, red
• Melting Point: ≥270 °C
• Solubility: H2O: soluble10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Highly selective and potent TrkA kinase inhibitor. Orally active. IC50 = 2 nM
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline

Description (简体中文)

Biochem/physiol Actions
Highly selective and potent TrkA kinase inhibitor. Orally active. IC50 = 2 nM
Legal Information
Sold for research purposes under agreement from Glaxo-Smith-Kline