1-Deoxy-D-xylulose

• Catalog No.: 14764
• CAS Number: 60299-43-6
• M. F.: C5H10O4
• M. W.: 134.1305
• Purity: ≥80% (TLC)

SYNONYMS

• IUPAC name: (3S,4R)-3,4,5-trihydroxypentan-2-one
• IUPAC Traditional name: 1-deoxy-D-xylulose
• Synonyms: 1-Deoxy-D-threo-2-pentulose; (3S,4R)-3,4,5-Trihydroxy-2-pentanone

DATABASE IDS

• CAS Number: 60299-43-6
• MDL Number: MFCD08460011

PROPERTIES

• Empirical Formula (Hill Notation): C5H10O4
• Purity: ≥80% (TLC)
• Optical Rotation: [α]/D +31.0±3.0°, c = 1 in H2O
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Metabolite of the non-mevalonate pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.
Linkage
In E. coli, 1-deoxy-D-xylulose is converted into 1-deoxy-D-xylulose 5-phosphate by phosphorylation of the C-5 hydroxy group by D-xylulokinase. 1

Description (简体中文)

Biochem/physiol Actions
Metabolite of the non-mevalonate pathway, generally found in prokaryotes, as precursor to isoprenoids as well as non-isoprenoids like vitamins. As this pathway is not present in humans, it is of interest for the development of bacterium-specific drugs in the search for treatments of infectious diseases.
Linkage
In E. coli, 1-deoxy-D-xylulose is converted into 1-deoxy-D-xylulose 5-phosphate by phosphorylation of the C-5 hydroxy group by D-xylulokinase. 1