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NSC 295642

Catalog No. N9413 Name Sigma Aldrich
CAS Number 77111-29-6 Website http://www.sigmaaldrich.com
M. F. C15H14ClCuN3S2 Telephone 1-800-521-8956
M. W. 399.42076 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154391

SYNONYMS

IUPAC name
2-(1-{2-[(benzylsulfanyl)[(chlorocuprio)sulfanyl]methylidene]hydrazin-1-ylidene}ethyl)pyridine
IUPAC Traditional name
2-(1-{2-[(benzylsulfanyl)[(chlorocuprio)sulfanyl]methylidene]hydrazin-1-ylidene}ethyl)pyridine
Synonyms
[1-(2-pyridinyl)ethylidene]-Hydrazinecarbodithioic acid, phenylmethyl ester, copper complex
Bis-[chloro[phenylmethyl [1-(2-pyridinyl)ethylidene]hydrazinecarbodithioato-N2,N2′,S1’]-copper]
Cu(II) complex of the Schiff base product of condensation of S-benzyl dithiocarbazate and 2-acetylpyridine

DATABASE IDS

CAS Number 77111-29-6

PROPERTIES

Empirical Formula (Hill Notation) C30H28Cl2Cu2N6S4
Purity ≥98% (HPLC)
Apperance dark green solid
Solubility DMSO: >5 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
Safety Statements 26-36/37
German water hazard class 3

DETAILS

Description (简体中文)
Biochem/physiol Actions
NSC 295642 is a potent inhibitor of cell migration. Cell migration is a basic biological process involved in a range of normal and pathological events, including wound healing, embryonic and tissue development, immune function and inflammation, angiogenesis and tumor metastasis. Therefore, cell migration can be adapted as an important biological tool to monitor several physiological processes as well as development of cancer. Accordingly, a potent inhibitor of cell migration, such as NSC 295642 can elucidate the intrinsic molecular mechanism of many biochemical events.
Description (English)
Biochem/physiol Actions
NSC 295642 is a potent inhibitor of cell migration. Cell migration is a basic biological process involved in a range of normal and pathological events, including wound healing, embryonic and tissue development, immune function and inflammation, angiogenesis and tumor metastasis. Therefore, cell migration can be adapted as an important biological tool to monitor several physiological processes as well as development of cancer. Accordingly, a potent inhibitor of cell migration, such as NSC 295642 can elucidate the intrinsic molecular mechanism of many biochemical events.

REFERENCES