NSC 295642

• Catalog No.: N9413
• CAS Number: 77111-29-6
• M. F.: C15H14ClCuN3S2
• M. W.: 399.42076
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-(1-{2-[(benzylsulfanyl)[(chlorocuprio)sulfanyl]methylidene]hydrazin-1-ylidene}ethyl)pyridine
• IUPAC Traditional name: 2-(1-{2-[(benzylsulfanyl)[(chlorocuprio)sulfanyl]methylidene]hydrazin-1-ylidene}ethyl)pyridine
• Synonyms: [1-(2-pyridinyl)ethylidene]-Hydrazinecarbodithioic acid, phenylmethyl ester, copper complex; Bis-[chloro[phenylmethyl [1-(2-pyridinyl)ethylidene]hydrazinecarbodithioato-N2,N2′,S1’]-copper]; Cu(II) complex of the Schiff base product of condensation of S-benzyl dithiocarbazate and 2-acetylpyridine

DATABASE IDS

• CAS Number: 77111-29-6

PROPERTIES

• Empirical Formula (Hill Notation): C30H28Cl2Cu2N6S4
• Purity: ≥98% (HPLC)
• Apperance: dark green solid
• Solubility: DMSO: >5 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36/37
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
NSC 295642 is a potent inhibitor of cell migration. Cell migration is a basic biological process involved in a range of normal and pathological events, including wound healing, embryonic and tissue development, immune function and inflammation, angiogenesis and tumor metastasis. Therefore, cell migration can be adapted as an important biological tool to monitor several physiological processes as well as development of cancer. Accordingly, a potent inhibitor of cell migration, such as NSC 295642 can elucidate the intrinsic molecular mechanism of many biochemical events.

Description (English)

Biochem/physiol Actions
NSC 295642 is a potent inhibitor of cell migration. Cell migration is a basic biological process involved in a range of normal and pathological events, including wound healing, embryonic and tissue development, immune function and inflammation, angiogenesis and tumor metastasis. Therefore, cell migration can be adapted as an important biological tool to monitor several physiological processes as well as development of cancer. Accordingly, a potent inhibitor of cell migration, such as NSC 295642 can elucidate the intrinsic molecular mechanism of many biochemical events.