Sulfaphenazole

• Catalog No.: UC166
• CAS Number: 526-08-9
• M. F.: C15H14N4O2S
• M. W.: 314.36226
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-amino-N-(1-phenyl-1H-pyrazol-5-yl)benzene-1-sulfonamide
• IUPAC Traditional name: merian
• Synonyms: 4-Amino-N-(1-phenyl-1H-pyrazol-5-yl)benzenesulfonamide

DATABASE IDS

• CAS Number: 526-08-9
• PubChem SID: 24724643
• EC Number: 208-384-3
• MDL Number: MFCD00057226

PROPERTIES

• Empirical Formula (Hill Notation): C15H14N4O2S
• Purity: ≥98% (HPLC)
• Gene Information: human ... CYP2C18(1562), CYP2C19(1557), CYP2C9(1559)
• Apperance: white to light yellow
• Melting Point: 179-183 °C
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: DA9520000
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.

Description (简体中文)

Biochem/physiol Actions
Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release.