Ketoconazole

• Catalog No.: UC280
• CAS Number: 65277-42-1
• M. F.: C26H28Cl2N4O4
• M. W.: 531.43092

SYNONYMS

• IUPAC name: 1-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]ethan-1-one
• IUPAC Traditional name: (2R,4S)-ketoconazole
• Synonyms: (±)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine

DATABASE IDS

• CAS Number: 65277-42-1
• PubChem SID: 24724652
• MDL Number: MFCD00058579
• EC Number: 265-667-4

PROPERTIES

• Empirical Formula (Hill Notation): C26H28Cl2N4O4
• Gene Information: human ... ABCB1(5243), CYP11B1(1584), CYP11B2(1585), CYP17A1(1586), CYP19A1(1588), CYP1A2(1544), CYP24A1(1591), CYP26A1(1592), CYP3A4(1576), CYP51A1(1595), KCNH1(3756)mouse ... Abcb1a(18671), Abcb1b(18669)rat ... Alox5(25290), Cyp17a1(25146), Cyp51(25427), Cyp7a1(25428)
• Apperance: white to light yellow
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H360F-H373-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
• GHS Precautionary statements: P201-P273-P301 + P310-P308 + P313-P501
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 60-25-48/22-50/53
• RTECS: TK7912300
• Safety Statements: 53-45-60-61
• Storage Temperature: 2-8°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
CYP3A4 inhibitor
Biochem/physiol Actions
Antifungal agent

Description (简体中文)

Application
CYP3A4 inhibitor
Biochem/physiol Actions
Antifungal agent