Topotecan hydrochloride hydrate

• Catalog No.: T2705
• CAS Number: 123948-87-8(freebase)
• M. F.: C23H23N3O5
• M. W.: 421.44582
• Purity: ≥98% (HPLC and enzymatic)
• Storage: desiccated

SYNONYMS

• IUPAC name: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.0^2,^1^1.0^4,^9.0^1^5,^2^0]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaene-14,18-dione
• IUPAC Traditional name: topotecan
• Synonyms: hycamptamine hydrochloride hydrate; 9-[(dimethylamino)methyl]-10-hydroxy-(20S)-camptothecin hydrochloride hydrate; NSC-609669 hydrochloride hydrate; SKF-104864A hydrochloride hydrate

DATABASE IDS

• CAS Number: 123948-87-8(freebase)
• MDL Number: MFCD00870670

PROPERTIES

• Empirical Formula (Hill Notation): C23H23N3O5 · xHCl · yH2O
• Purity: ≥98% (HPLC and enzymatic)
• Apperance: yellow powder
• Solubility: DMSO: ≥20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H341
• GHS Precautionary statements: P281
• RID/ADR: UN 2811 6.1/PG 3
• Risk Statements: 46-48
• Safety Statements: 22-36
• Storage Condition: desiccated
• Storage Condition: protect from light
• Storage Temperature: -20°C
• Hazard Class: 6.1
• UN Number: 2811
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Topotecan is a topoisomerase I inhibitor and an apoptosis inducer. It is a potent antineoplastic agent.

Description (简体中文)

Biochem/physiol Actions
Topotecan is a topoisomerase I inhibitor and an apoptosis inducer. It is a potent antineoplastic agent.