ARC 239 dihydrochloride hydrate

• Catalog No.: A5736
• CAS Number: 67339-62-2(freebase)
• M. F.: C24H33Cl2N3O4
• M. W.: 498.44252
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 2-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline-1,3-dione hydrate dihydrochloride
• IUPAC Traditional name: 2-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-4,4-dimethylisoquinoline-1,3-dione hydrate dihydrochloride
• Synonyms: (2-[2-[4-(o-Methoxyphenyl)piperazin-1-yl]ethyl]-4,4-dimethyl-1,3-(2H,4H)-isoquinolinedione dihydrochloride hydrate

DATABASE IDS

• CAS Number: 67339-62-2(freebase)
• MDL Number: MFCD16875414

PROPERTIES

• Empirical Formula (Hill Notation): C24H29N3O3·2HCl · xH2O
• Purity: ≥98% (HPLC)
• Apperance: white to off-white powder
• Solubility: H2O: >5 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H400
• European Hazard Symbols: Harmful (Xn)
• European Hazard Symbols: Nature polluting (N)
• GHS Precautionary statements: P273
• RID/ADR: UN 3077 9/PG 3
• Risk Statements: 22-50/53
• Safety Statements: 60-61
• Storage Temperature: 2-8°C
• Hazard Class: 9
• UN Number: 3077
• Packing Group: 3
• German water hazard class: 3

DETAILS

Description (English)

Application
ARC 239 is a potent α-adrenoceptor blocking drug, competitively antagonizing pressor responses to adrenaline and inhibiting pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium.
Biochem/physiol Actions
ARC 239 is a selective α-2B adrenergic blocker. Although ARC-239, like prazosin, also has some alpha-1 antagonist activity, it is used most commomly to differentiate alpha-2A/D from alpha-2B and alpha-2C subtypes rather than for any alpha-1 inhibition..

Description (简体中文)

Application
ARC 239 is a potent α-adrenoceptor blocking drug, competitively antagonizing pressor responses to adrenaline and inhibiting pressor responses to noradrenaline, phenylephrine, tyramine, and dimethylphenylpiperazinium.
Biochem/physiol Actions
ARC 239 is a selective α-2B adrenergic blocker. Although ARC-239, like prazosin, also has some alpha-1 antagonist activity, it is used most commomly to differentiate alpha-2A/D from alpha-2B and alpha-2C subtypes rather than for any alpha-1 inhibition..