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LY255283

Catalog No. L1920 Name Sigma Aldrich
CAS Number 117690-79-6 Website http://www.sigmaaldrich.com
M. F. C19H28N4O3 Telephone 1-800-521-8956
M. W. 360.45062 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 154358

SYNONYMS

IUPAC name
1-(5-ethyl-2-hydroxy-4-{[6-methyl-6-(1H-1,2,3,4-tetrazol-5-yl)heptyl]oxy}phenyl)ethan-1-one
IUPAC Traditional name
1-(5-ethyl-2-hydroxy-4-{[6-methyl-6-(1H-1,2,3,4-tetrazol-5-yl)heptyl]oxy}phenyl)ethanone
Synonyms
1-(5-Ethyl-2-hydroxy-4-(6-methyl-6-(1H-tetrazol-5-yl)heptyloxy)phenyl)ethanone

DATABASE IDS

CAS Number 117690-79-6
MDL Number MFCD00876422

PROPERTIES

Empirical Formula (Hill Notation) C19H28N4O3
Purity ≥98% (HPLC)
Apperance off-white to light yellow powder
Solubility DMSO: >20 mg/mL
MSDS Link Download
Storage Temperature -20°C
German water hazard class 2

DETAILS

Description (English)
Biochem/physiol Actions
LY255283 is a competitive leukotriene B4 receptor antagonist, with an IC50 of about 100 nM. It is somewhat selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 reduces airway obstruction in animal models of asthma.1
Description (简体中文)
Biochem/physiol Actions
LY255283 is a competitive leukotriene B4 receptor antagonist, with an IC50 of about 100 nM. It is somewhat selective for the BLT2 receptor, since IC50 values at the BLT1 receptor are >10 μM. LY255283 reduces airway obstruction in animal models of asthma.1

REFERENCES