Cryptotanshinone

• Catalog No.: 79852
• CAS Number: 35825-57-1
• M. F.: C19H20O3
• M. W.: 296.3603
• Purity: ≥90% (HPLC)

SYNONYMS

• IUPAC name: (14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
• IUPAC Traditional name: (14R)-6,6,14-trimethyl-12-oxatetracyclo[8.7.0.0^2,^7.0^1^1,^1^5]heptadeca-1(10),2(7),8,11(15)-tetraene-16,17-dione
• Synonyms: (R)-(-)-1,6,6-Trimethyl-1,2,6,7,8,9-hexahydrophenanthro[1,2-b]furan-10,11-dione

DATABASE IDS

• Beilstein Number: 5445400
• MDL Number: MFCD07636810
• CAS Number: 35825-57-1

PROPERTIES

• Empirical Formula (Hill Notation): C19H20O3
• Purity: ≥90% (HPLC)
• Optical Rotation: [α]/D -85.0±3.0°, c = 0.1 in chloroform
• GHS Signal Word: Danger
• GHS Hazard statements: H301-H410
• European Hazard Symbols: Toxic (T)
• European Hazard Symbols: Nature polluting (N)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P273-P301 + P310-P501
• Risk Statements: 25-50/53
• RTECS: SF8282645
• Safety Statements: 45-60-61
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4

Description (简体中文)

Biochem/physiol Actions
Cryptotanshinone is an antibacterial and anti-inflammatory compound originally extracted from the roots of Salvia miltiorrhiaz (danshen). Cryptotanshinone has been found to inhibit HIF activation1 and to inhibit macrophage migration negatively regulate the PI3K pathway.2,3 It has demonstrated activity against several strains of Staphylococcus aureus.4