Tioconazole

• Catalog No.: 03907
• CAS Number: 65899-73-2
• M. F.: C16H13Cl3N2OS
• M. W.: 387.71122
• Purity: ≥96.5% (HPLC)

SYNONYMS

• IUPAC name: 1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
• IUPAC Traditional name: tioconazole
• Synonyms: Thioconazole; 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole

DATABASE IDS

• MDL Number: MFCD00057276
• EC Number: 265-973-8
• CAS Number: 65899-73-2

PROPERTIES

• Empirical Formula (Hill Notation): C16H13Cl3N2OS
• Purity: ≥96.5% (HPLC)
• Purity: 96.5-103.5% (NT)
• Purity: 97%
• GHS Signal Word: Warning
• GHS Hazard statements: H302-H413
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: NI4480000
• German water hazard class: 3

DETAILS

Description (English)

Application
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast. It is used to study the synergistic mechanisms of antifungals on Candida albicans 1 as well as significant drug-drug interactions in vivo2.
Biochem/physiol Actions
Tioconazole is an antifungal that is more active than fluconazole or voriconazole against Candida glabrata mutant strains.3 Its mechanism of action is through membrane disruption and loss of intracellular ATP.4

Description (简体中文)

Application
Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast. It is used to study the synergistic mechanisms of antifungals on Candida albicans 1 as well as significant drug-drug interactions in vivo2.
Biochem/physiol Actions
Tioconazole is an antifungal that is more active than fluconazole or voriconazole against Candida glabrata mutant strains.3 Its mechanism of action is through membrane disruption and loss of intracellular ATP.4