Ricobendazole

• Catalog No.: 19953
• CAS Number: 54029-12-8
• M. F.: C12H15N3O3S
• M. W.: 281.3308
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: methyl N-[5-(propane-1-sulfinyl)-1H-1,3-benzodiazol-2-yl]carbamate
• IUPAC Traditional name: (+-)-albendazole sulfoxide
• Synonyms: Albendazole oxide; Methyl [5-(propane-1-sulfinyl)-1H-benzoimidazol-2-yl]-carbamate; Albendazole sulfoxide

DATABASE IDS

• Beilstein Number: 677664
• CAS Number: 54029-12-8
• MDL Number: MFCD00797922

PROPERTIES

• Empirical Formula (Hill Notation): C12H15N3O3S
• Purity: ≥98% (HPLC)
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• Risk Statements: 22
• RTECS: FD1080000
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.2
Application
Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole 1. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.2

Description (简体中文)

Biochem/physiol Actions
Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.2
Application
Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole 1. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.2