A3 hydrochloride

• Catalog No.: A1980
• CAS Number: 78957-85-4
• M. F.: C12H14Cl2N2O2S
• M. W.: 321.22276
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
• IUPAC Traditional name: N-(2-aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride
• Synonyms: N-(2-Aminoethyl)-5-chloronaphthalene-1-sulfonamide hydrochloride

DATABASE IDS

• MDL Number: MFCD00077311
• CAS Number: 78957-85-4
• PubChem SID: 24890609

PROPERTIES

• Empirical Formula (Hill Notation): C12H13ClN2O2S · HCl
• Purity: ≥98% (HPLC)
• Apperance: white solid
• Solubility: DMSO: soluble24 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM).

Description (简体中文)

Biochem/physiol Actions
Non-selective casein kinase (CK) inhibitor. A shorter alkyl chain derivative of W-7 that inhibits casein kinase I (Ki = 80 μM), casein kinase II (Ki = 5.1 μM), myosin light chain kinase (Ki = 7.4 μM), protein kinase A (Ki = 4.3 μM), protein kinase C (Ki= 47 μM), and protein kinase G (Ki = 3.8 μM).