Ibutilide hemifumarate salt

• Catalog No.: I9910
• CAS Number: 122647-32-9
• M. F.: C44H76N4O10S2
• M. W.: 885.22504
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: bis(N-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide); but-2-enedioic acid
• IUPAC Traditional name: butenedioic acid; bis(ibutilide)
• Synonyms: Corvert; (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]-methanesulfonamide hemifumarate salt

DATABASE IDS

• MDL Number: MFCD01715410
• CAS Number: 122647-32-9

PROPERTIES

• Empirical Formula (Hill Notation): C20H36N2O3S · 0.5C4H4O4
• Purity: ≥98% (HPLC)
• Apperance: off-white to tan solid
• Solubility: H2O: >20 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H302
• European Hazard Symbols: Harmful (Xn)
• Risk Statements: 22
• Storage Temperature: room temp
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.

Description (简体中文)

Biochem/physiol Actions
Ibutilide hemifumarate salt is considered a new generation "pure" Class III antiarrhythmic agent. Ibutilide binds to and alters the activity of hERG potassium channels, delayed inward rectifier potassium (IKr) channels and L-type (dihydropyridine sensitive) calcium channels.