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Hydroxyflutamide

Catalog No. H4166 Name Sigma Aldrich
CAS Number 52806-53-8 Website http://www.sigmaaldrich.com
M. F. C11H11F3N2O4 Telephone 1-800-521-8956
M. W. 292.2112496 Fax
Purity ≥98% (HPLC) Email
Storage desiccated Chembase ID: 94067

SYNONYMS

IUPAC name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
IUPAC Traditional name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Synonyms
2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-propanamide
Sch 16423
Hydroxyniphtholide
a,a,a-Trifluoro-2-methyl-4′-nitro-m-lactotoluidide
2-Hydroxyflutamide

DATABASE IDS

MDL Number MFCD00563126
CAS Number 52806-53-8

PROPERTIES

Empirical Formula (Hill Notation) C11H11F3N2O4
Purity ≥98% (HPLC)
Apperance white to tan powder
Solubility DMSO: >10 mg/mL
GHS Pictograms GHS07
GHS Signal Word Warning
GHS Hazard statements H315-H319-H335
European Hazard Symbols Irritant Irritant (Xi)
MSDS Link Download
GHS Precautionary statements P261-P305 + P351 + P338
Risk Statements 36/37/38
RTECS TX1466250
Safety Statements 26-36/37/39
Storage Condition desiccated
Storage Temperature room temp
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Hydroxflutamide is an AR antagonist. Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. Hydroxyflutamide is an androgen antagonist with publications going back to 1981. It is one of a few gold standard AR antagonists; activities of new antagonists are measured against hydroxyflutamide.
Description (简体中文)
Biochem/physiol Actions
Hydroxflutamide is an AR antagonist. Androgen receptors (ARs) are nuclear hormone receptors/transcription factors. Hydroxyflutamide is an androgen antagonist with publications going back to 1981. It is one of a few gold standard AR antagonists; activities of new antagonists are measured against hydroxyflutamide.

REFERENCES