BD 1047 dihydrobromide

• Catalog No.: B8562
• CAS Number: 138356-21-5
• M. F.: C13H22Br2Cl2N2
• M. W.: 437.04118
• Purity: ≥95% (HPLC)

SYNONYMS

• IUPAC name: [2-(3,4-dichlorophenyl)ethyl][2-(dimethylamino)ethyl]methylamine dihydrobromide
• IUPAC Traditional name: [2-(3,4-dichlorophenyl)ethyl][2-(dimethylamino)ethyl]methylamine dihydrobromide
• Synonyms: BD 1047 dihydrobromide

DATABASE IDS

• MDL Number: MFCD00792739
• CAS Number: 138356-21-5

PROPERTIES

• Empirical Formula (Hill Notation): C13H20Cl2N2 · 2 HBr
• Purity: ≥95% (HPLC)
• Apperance: white powder
• Solubility: H2O: >5 mg/mL
• GHS Signal Word: Danger
• GHS Hazard statements: H315-H318-H335
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P261-P280-P305 + P351 + P338
• Risk Statements: 37/38-41
• Safety Statements: 26-36/37
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
BD-1047 is a selective, putative σ receptor antagonist with antidystonic activity. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. Though s receptor antagonism is consistent with antipsychotic, especially anti-schizophrenic, activity, BD-1047 shows only modest activity in animal screens for antipsychotics.1

Description (简体中文)

Biochem/physiol Actions
BD-1047 is a selective, putative σ receptor antagonist with antidystonic activity. BD-1047 has >50-fold selectivity at σ1 over σ2 and also >100-fold selectivity over opiate, phencyclidine, muscarinic, dopamine, α1- & α2-adrenoceptor, 5-HT1, and 5-HT2. Though s receptor antagonism is consistent with antipsychotic, especially anti-schizophrenic, activity, BD-1047 shows only modest activity in animal screens for antipsychotics.1