AICAR

• Catalog No.: A9978
• CAS Number: 2627-69-2
• M. F.: C9H14N4O5
• M. W.: 258.23126
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-imidazole-4-carboxamide
• IUPAC Traditional name: acadesine
• Synonyms: 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside; N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide; Acadesine

DATABASE IDS

• EC Number: 220-097-5
• CAS Number: 2627-69-2
• MDL Number: MFCD00869751
• PubChem SID: 24724407

PROPERTIES

• Empirical Formula (Hill Notation): C9H14N4O5
• Purity: ≥98% (HPLC)
• Shipped in: dry ice
• Apperance: tan powder
• Melting Point: 214-215 °C
• Solubility: H2O: >7 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Description (简体中文)

Frequently Asked Questions
Live Chat and Frequently Asked Questions are available for this Product.
Biochem/physiol Actions
AICAR is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with AICAR mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.