FTI-277 trifluoroacetate salt

• Catalog No.: F9803
• CAS Number: 170006-73-2(freebase)
• M. F.: C24H30F3N3O5S2
• M. W.: 561.6373096
• Purity: ≥95% (HPLC)
• Storage: desiccated

SYNONYMS

• IUPAC name: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-phenylphenyl)formamido]-4-(methylsulfanyl)butanoate
• IUPAC Traditional name: trifluoroacetic acid methyl (2S)-2-[(4-{[(2R)-2-amino-3-sulfanylpropyl]amino}-2-phenylphenyl)formamido]-4-(methylsulfanyl)butanoate
• Synonyms: N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-phenylbenzoyl]methionine methyl ester trifluoroacetate salt

DATABASE IDS

• MDL Number: MFCD06795840
• CAS Number: 170006-73-2(freebase)

PROPERTIES

• Empirical Formula (Hill Notation): C22H29N3O3S2 · xC2HF3O2
• Purity: ≥95% (HPLC)
• Shipped in: wet ice
• Apperance: amorphous semi-solid
• Solubility: H2O: ≥2 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H315-H319-H335
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P261-P305 + P351 + P338
• Risk Statements: 36/37/38
• Safety Statements: 26-36
• Storage Condition: desiccated
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Highly potent (pM/nM) Ras CAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. Inhibitor of farnesyltransferase (Ftase) IC50 = 50 nM.
Packaging
Very hygroscopic material, package in a dry room with deoxygenated MeOH and pump down the solvent. Store with desiccant.

Description (简体中文)

Biochem/physiol Actions
Highly potent (pM/nM) Ras CAAX peptidomimetic which antagonizes both H and K-Ras oncogenic signaling. Inhibitor of farnesyltransferase (Ftase) IC50 = 50 nM.
包装
Very hygroscopic material, package in a dry room with deoxygenated MeOH and pump down the solvent. Store with desiccant.