8-AHA-cAMP

• Catalog No.: A2104
• CAS Number: 39824-30-1
• M. F.: C16H26N7O6P
• M. W.: 443.394701
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: (4aR,6R,7R,7aS)-6-{6-amino-8-[(6-aminohexyl)amino]-9H-purin-9-yl}-2,7-dihydroxy-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-one
• IUPAC Traditional name: (4aR,6R,7R,7aS)-6-{6-amino-8-[(6-aminohexyl)amino]purin-9-yl}-2,7-dihydroxy-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-one
• Synonyms: 8-(6-Aminohexyl)aminoadenosine-3′,5′-cyclic monophosphate

DATABASE IDS

• CAS Number: 39824-30-1
• PubChem SID: 24724386
• MDL Number: MFCD00057125

PROPERTIES

• Empirical Formula (Hill Notation): C16H26N7O6P
• Packaging: vial of 25 μmol
• Purity: ≥98% (HPLC)
• Shipped in: dry ice
• Apperance: white powder
• Solubility: dilute NaOH: soluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -70°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cAMP analog with preference for site B of RI of cAMP-dependent protein kinase. In combination with 8-piperidino-cAMP, which selects site A of RI and site B of RII, selective synergistic activation of protein kinase A type I can be obtained.

Description (简体中文)

Biochem/physiol Actions
Selective cAMP-dependent protein kinase (PKA) activator. Site selective cAMP analog with preference for site B of RI of cAMP-dependent protein kinase. In combination with 8-piperidino-cAMP, which selects site A of RI and site B of RII, selective synergistic activation of protein kinase A type I can be obtained.