PET-cGMP

• Catalog No.: P0622
• CAS Number: 78080-27-0
• M. F.: C18H15N5NaO7P
• M. W.: 467.304531
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: sodium (4aR,6R,7R,7aS)-7-hydroxy-2-oxo-6-{9-oxo-6-phenyl-3H,5H,9H-imidazo[1,2-a]purin-3-yl}-hexahydro-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• IUPAC Traditional name: sodium (4aR,6R,7R,7aS)-7-hydroxy-2-oxo-6-{9-oxo-6-phenyl-5H-imidazo[1,2-a]purin-3-yl}-tetrahydro-4H-1,3,5,2λ^5-furo[3,2-d][1,3,2λ^5]dioxaphosphinin-2-olate
• Synonyms: β-Phenyl-1,N2-ethenoguanosine 3′,5′-monophosphate sodium salt

DATABASE IDS

• PubChem SID: 24724570
• CAS Number: 78080-27-0
• MDL Number: MFCD04118064

PROPERTIES

• Empirical Formula (Hill Notation): C18H15N5O7PNa
• Packaging: pkg of 10 μmol
• Purity: ≥98% (HPLC)
• Shipped in: dry ice
• Apperance: white solid
• Solubility: H2O: ~10 mmol
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -70°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
cGMP-dependent protein kinase (PKG I and PKG II) activator. Potent membrane permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase. Common stimulators such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtype Iα.

Description (简体中文)

Biochem/physiol Actions
cGMP-dependent protein kinase (PKG I and PKG II) activator. Potent membrane permeant activator of both isozymes I α and I β of cGMP-dependent protein kinase. Common stimulators such as 8-Br-cGMP or 8-pCPT-cGMP mainly activate kinase subtype Iα.