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Mirtazapine

Catalog No. M0443 Name Sigma Aldrich
CAS Number 85650-52-8 Website http://www.sigmaaldrich.com
M. F. C17H19N3 Telephone 1-800-521-8956
M. W. 265.35286 Fax
Purity ≥98% (HPLC) Email
Storage Chembase ID: 254

SYNONYMS

IUPAC name
5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene
IUPAC Traditional name
mirtazapine
Synonyms
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine

DATABASE IDS

PubChem SID 24724531
MDL Number MFCD00865427
CAS Number 85650-52-8

PROPERTIES

Empirical Formula (Hill Notation) C17H19N3
Purity ≥98% (HPLC)
Gene Information human ... ADRA2A(150), ADRA2C(152), DRD2(1813), DRD3(1814), DRD4(1815), HRH1(3269), HTR1A(3350), HTR2A(3356), HTR2C(3358), HTR7(3363)mouse ... Slc6a2(20538)rat ... Adra1a(29412), Drd1a(24316), Drd2(24318), Htr1a(24473), Htr2a(29595), Htr2c(25187), Slc6a3(24898), Slc6a4(25553)
Apperance white powder
Solubility DMSO: soluble ~8 mg/mL
MSDS Link Download
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
German water hazard class 3

DETAILS

Description (English)
Biochem/physiol Actions
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.
Description (简体中文)
Biochem/physiol Actions
Mirtazapine is a noradrenergic and specific serotonergic antidepressant (NaSSA). Mirtazapine agonizes selective adrenergic and serotonergic receptors so that both NE release and 5-HT1A mediated serotonergic signaling are increased.

REFERENCES