BTA-1

• Catalog No.: B9934
• CAS Number: 439858-28-3
• M. F.: C14H12N2S
• M. W.: 240.32348
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-(1,3-benzothiazol-2-yl)-N-methylaniline
• IUPAC Traditional name: 4-(1,3-benzothiazol-2-yl)-N-methylaniline
• Synonyms: 2-(4′-Methylaminophenyl)benzothiazole

DATABASE IDS

• CAS Number: 439858-28-3
• PubChem SID: 24724428
• MDL Number: MFCD04974146

PROPERTIES

• Empirical Formula (Hill Notation): C14H12N2S
• Purity: ≥98% (HPLC)
• Gene Information: human ... APP(351)
• Apperance: yellow solid
• Solubility: DMSO: soluble ~10 mg/mL
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (简体中文)

Biochem/physiol Actions
BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier.

Description (English)

Biochem/physiol Actions
BTA-1 is a probe for β-amyloid aggregates; fluorescent thioflavin-T derivative; exhibits high affinity for amyloid deposits; displays 50-fold higher affinity than thioflavin-T; selectively stains cerebral plaques and cerebrovascular amyloid deposits in the brains of PS1/APP transgenic mice, as well as Aβ fibrils in postmortem brain tissue obtained from AD patients; crosses the blood brain barrier.