(-)-Deguelin

• Catalog No.: D0817
• CAS Number: 522-17-8
• M. F.: C23H22O6
• M. W.: 394.41718
• Purity: >98% (HPLC)

SYNONYMS

• IUPAC name: (1S,14S)-17,18-dimethoxy-7,7-dimethyl-2,8,21-trioxapentacyclo[12.8.0.0^3,^1^2.0^4,^9.0^1^5,^2^0]docosa-3(12),4(9),5,10,15,17,19-heptaen-13-one
• IUPAC Traditional name: deguelin
• Synonyms: (7aS,13aS)-13,13a-Dihydro-9,10-dimethoxy-3,3-dimethyl-3H-bis[1]benzopyrano[3,4-b:6′,5′-e]pyran-7(7aH)-one

DATABASE IDS

• MDL Number: MFCD01740600
• CAS Number: 522-17-8

PROPERTIES

• Empirical Formula (Hill Notation): C23H22O6
• Purity: >98% (HPLC)
• Apperance: white to yellow solid
• Melting Point: 85-87 °C(lit.)
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: insoluble
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• RTECS: DX1500000
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Inhibitor of activated Akt. Does not affect MAPK, ERK1/2, or JNK. Anticancer, chemoprotective agent.

Description (简体中文)

Biochem/physiol Actions
Inhibitor of activated Akt. Does not affect MAPK, ERK1/2, or JNK. Anticancer, chemoprotective agent.