APHA Compound 8

• Catalog No.: A2478
• CAS Number: 676599-90-9
• M. F.: C16H16N2O3
• M. W.: 284.30984
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: N-hydroxy-3-[1-methyl-4-(2-phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide
• IUPAC Traditional name: N-hydroxy-3-[1-methyl-4-(2-phenylacetyl)pyrrol-2-yl]prop-2-enamide
• Synonyms: 3-(1-Methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide

DATABASE IDS

• CAS Number: 676599-90-9

PROPERTIES

• Empirical Formula (Hill Notation): C16H16N2O3
• Purity: ≥98% (HPLC)
• Apperance: solid
• Solubility: DMSO: >10 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Danger
• GHS Hazard statements: H302-H317-H318
• European Hazard Symbols: Harmful (Xn)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Faceshields, Gloves
• GHS Precautionary statements: P280-P305 + P351 + P338
• Risk Statements: 22-41-43
• Safety Statements: 26-36/37/39
• Storage Temperature: 2-8°C
• German water hazard class: 2

DETAILS

Description (English)

Biochem/physiol Actions
One of a class of aroyl pyrrole hydroxy amide (APHA) compounds showing histone deacetylase (HDAC) inhibition, Compound 8 is the most potent and HDAC class I-selective.1

Description (简体中文)

Biochem/physiol Actions
One of a class of aroyl pyrrole hydroxy amide (APHA) compounds showing histone deacetylase (HDAC) inhibition, Compound 8 is the most potent and HDAC class I-selective.1