ISCK03

• Catalog No.: I6410
• CAS Number: 945526-43-2
• M. F.: C19H21N3O2S
• M. W.: 355.45394
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 4-tert-butyl-N-[4-(1H-imidazol-1-yl)phenyl]benzene-1-sulfonamide
• IUPAC Traditional name: 4-tert-butyl-N-[4-(imidazol-1-yl)phenyl]benzenesulfonamide
• Synonyms: Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[4-(1H-imidazol-1-yl)phenyl]; [4-t-Butylphenyl]-N-(4-imidazol-1-yl phenyl)sulfonamide

DATABASE IDS

• CAS Number: 945526-43-2
• MDL Number: MFCD12031591

PROPERTIES

• Empirical Formula (Hill Notation): C19H21N3O2S
• Purity: ≥98% (HPLC)
• Apperance: yellow solid
• Solubility: DMSO: ≥20 mg/mL
• Solubility: H2O: insoluble
• GHS Signal Word: Warning
• GHS Hazard statements: H319
• European Hazard Symbols: Irritant (Xi)
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 36
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. ISCK03 inhibits SCF (stem cell factor)-induced c-kit phosphorylation in 501mel human melanoma cells. Complete inhibition was observed with 1 and 5 μM ISCK03.

Description (简体中文)

Biochem/physiol Actions
ISCK03 inhibits in vitro phosphorylation of c-Kit in a dose dependent manner. ISCK03 inhibits SCF (stem cell factor)-induced c-kit phosphorylation in 501mel human melanoma cells. Complete inhibition was observed with 1 and 5 μM ISCK03.