SARS Protease Substrate

• Catalog No.: 07859
• CAS Number: 587886-51-9
• M. F.: C66H119N21O22S
• M. W.: 1590.84356
• Purity: ≥85% (HPLC)

SYNONYMS

• IUPAC name: (2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-hydroxypropanamido]-3-methylbutanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]-4-methylpentanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]acetamido}-4-methylpentanamido]-5-carbamimidamidopentanamido]hexanamido]-4-(methylsulfanyl)butanamido]propanoic acid
• IUPAC Traditional name: (2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S,3R)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-amino-3-methylbutanamido]-3-hydroxypropanamido]-3-methylbutanamido]-3-carbamoylpropanamido]-3-hydroxypropanamido]-3-hydroxybutanamido]-4-methylpentanamido]-4-carbamoylbutanamido]-3-hydroxypropanamido]acetamido}-4-methylpentanamido]-5-carbamimidamidopentanamido]hexanamido]-4-(methylsulfanyl)butanamido]propanoic acid
• Synonyms: L-Valyl-L-seryl-L-valyl-L-asparaginyl-L-seryl-L-threonyl-L-leucyl-L-glutaminyl-L-serylglycyl-L-leucyl-L-arginyl-L-lysyl-L-methionyl-L-alanine; Val-Ser-Val-Asn- Ser-Thr-Leu-Gln-Ser-Gly-Leu-Arg-Lys-Met-Ala

DATABASE IDS

• CAS Number: 587886-51-9
• MDL Number: MFCD08274404

PROPERTIES

• Empirical Formula (Hill Notation): C66H119N21O22S
• Purity: ≥85% (HPLC)
• Personal Protective Equipment: Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
• Storage Temperature: -20°C
• German water hazard class: 3

DETAILS

Description (English)

Application
Enzyme substrate for the assays of the SARS coronavirus main protease2
Biochem/physiol Actions
A study for determining substrate specificity for the SARS main protease indicated that the best substrates contained residues with high β-sheet propensity at positions P5 and P3., small hydrophobic residues at P4, hydrophobic residues without β-branching at residue P2 and a GLN for residue P1. 1

Description (简体中文)

Application
Enzyme substrate for the assays of the SARS coronavirus main protease2
Biochem/physiol Actions
A study for determining substrate specificity for the SARS main protease indicated that the best substrates contained residues with high β-sheet propensity at positions P5 and P3., small hydrophobic residues at P4, hydrophobic residues without β-branching at residue P2 and a GLN for residue P1. 1