RN-1747

• Catalog No.: R1033
• CAS Number: 1024448-59-6
• M. F.: C17H18ClN3O4S
• M. W.: 395.86052
• Purity: ≥98% (HPLC)

SYNONYMS

• IUPAC name: 1-benzyl-4-(4-chloro-2-nitrobenzenesulfonyl)piperazine
• IUPAC Traditional name: 1-benzyl-4-(4-chloro-2-nitrobenzenesulfonyl)piperazine
• Synonyms: 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine;; 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-piperazine

DATABASE IDS

• CAS Number: 1024448-59-6
• MDL Number: MFCD04154169

PROPERTIES

• Empirical Formula (Hill Notation): C17H18ClN3O4S
• Purity: ≥98% (HPLC)
• Apperance: light yellow to light tan powder
• Solubility: DMSO: ≥10 mg/mL
• GHS Signal Word: Warning
• GHS Hazard statements: H319
• European Hazard Symbols: Irritant (Xi)
• GHS Precautionary statements: P305 + P351 + P338
• Risk Statements: 36
• Safety Statements: 26
• Storage Temperature: 2-8°C
• German water hazard class: 1

DETAILS

Description (English)

Biochem/physiol Actions
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions.

Description (简体中文)

Biochem/physiol Actions
TRPV4, a close relative of the vanilloid receptor TRPV1, is activated by diverse modalities such as endogenous lipid ligands, hypotonicity, protein kinases and, possibly, mechanical inputs. TRPV4 is a nociceptor playing an important role in inflammatory and neuropathic mechanical hyperalgesia in rodent models apparently specifically activated under pathological conditions.