Ibandronate sodium salt

• Catalog No.: I5784
• CAS Number: 138844-81-2
• M. F.: C9H22NNaO7P2
• M. W.: 341.210772
• Purity: ≥97% (NMR)
• Storage: protect from light

SYNONYMS

• Title: Ibandronate 钠 一水合物
• IUPAC name: sodium hydrogen {1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropyl}phosphonate
• IUPAC Traditional name: sodium hydrogen 1-hydroxy-3-[methyl(pentyl)amino]-1-phosphonopropylphosphonate
• Synonyms: Boniva; (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid 钠 一水合物; (1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonic acid sodium; Bondronat

DATABASE IDS

• MDL Number: MFCD07197214
• CAS Number: 138844-81-2

PROPERTIES

• Empirical Formula (Hill Notation): C9H22NNaO7P2
• Purity: ≥97% (NMR)
• Apperance: white solid
• Solubility: H2O: >10 mg/mL
• Storage Condition: protect from light
• Storage Temperature: 2-8°C
• German water hazard class: 3

DETAILS

Description (English)

Biochem/physiol Actions
Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.

Description (简体中文)

Biochem/physiol Actions
Ibandronate sodium inhibits farnesyl diphosphate synthase (IC50 = 20 nM). Ibandronate sodium is also a bone resorption inhibitor. It has been investigated for in vitro anti-tumor effects, such as apoptosis induction, inhibitor of cell growth, inhibition of invasive behavior, and inhibition of angiogenesis and for its in vivo role in various cancers including breast and prostate cancers.